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In patients receiving levothyroxine, liotrix, or thyroid extract for primary hypothyroidism, serum free T 4 index (total serum T 4 and T 3 resin uptake) or serum free T 4 together with a serum thyroid-stimulating hormone (TSH) are the most useful tests for monitoring replacement therapy.
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However, some achieve a sense of wellbeing only when serum thyroid stimulating hormone is suppressed, when we take care to ensure that serum tri-iodothyronine is unequivocally normal.
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Over 12 percent of the patients at the Mayo Clinic's Department of Physical Medicine and Rehabilitation have this problem, and it is the third most common diagnosis by rheumatologists in the outpatient setting.
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Surgery and other medical interventions have become ever more effective, but they are not always beneficial: they can sustain, or even replace, failing vital functions, but that is not the same as promoting health.
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