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When taken faithfully, these drugs are usually very effective in controlling hyperthyroidism within a few weeks.
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Graves disease (like Hashimoto thyroiditis) sometimes occurs with other autoimmune disorders, including type 1 diabetes mellitus, vitiligo, premature graying of hair, pernicious anemia, connective tissue disorders, and polyglandular deficiency syndrome.
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Radioiodine should be a good treatment for your cat, especially if all of her other body functions are good (no kidney disease, etc).
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Most patients with Graves disease have circulating antithyroid peroxidase antibodies, and fewer have antithyroglobulin antibodies.
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In one study of 40 hyperthyroid cats (12), once-daily dosing was much less effective than use of twice-daily administration (the total daily dose given was the same in both groups of cats).
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Answer: This is probably something that your own doctor or endocrinologist could probably answer, but I will take a stab at this one in general terms.
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The boxed warning also states that propylthiouracil should be reserved for use in those who cannot tolerate other treatments such as methimazole, radioactive iodine, or surgery.
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The kind of treatment you have depends on your age, what is causing your hyperthyroidism, how much hormone your body is making, and other medical conditions you may have.
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RAI and surgery are permanent, irreversible treatments that almost always result in lifelong hypothyroidism for the patient.
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Over the 25 years since we first reported the use of methimazole for treatment of cats with hyperthyroidism (2), I have had repeated questions from veterinarians and cat owners about the use of once or twice-daily dosing regimes.
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