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One participant in the varenicline group had depression that was attributed to the study drug.
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National Cancer Institute, is a useful resource addressing smoking among middle-aged and older adults.
Advise patients to immediately stop taking varenicline if they develop agitation, hostility, aggressive behavior, depressed mood, or changes in behavior or thinking that are not typical for them, or if they develop suicidal ideation or behavior.
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If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online () or by phone (1-800-332-1088).
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Based on the evidence reviewed by the USPSTF, only minor adverse events related to ear acupuncture, ear acupressure, and other auriculotherapy were identified.
The USPSTF did not find any serious adverse events related to behavioral interventions for smoking cessation in pregnant women.
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Genetic background influences the effects of withdrawal from chronic nicotine on learning and high-affinity nicotinic acetylcholine receptor binding in the dorsal and ventral hippocampus.
Because of the variation and lack of regulatory oversight on the content of ENDS and the limited evidence available from well-designed studies, further research is clearly needed.
We did this review of reviews to help the USPSTF update its 2009 recommendation on interventions for tobacco cessation among adults.
If you quit smoking before you are 35, you will live about six years longer.
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Gonzales D, Rennard SI, Nides M, Oncken C, Azoulay S, Billing CB, Watsky EJ, Gong J, Williams KE, Reeves KR, et al: Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs sustained-release bupropion and placebo for smoking cessation: a randomized controlled trial.
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Evidence shows that Chronic Obstructive Pulmonary Disease is under-recognised, under-diagnosed and under-managed.
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All services offered to you as part of this study, including the medication, will be provided free of charge.
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However, previous use of NRT did not account for the between-country differences in the relative efficacy of varenicline at the end of treatment or through week 52.
The actions of nicotine and cocaine in a mouse model of anxiety.
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For people with severe COPD, inhaled corticosteroids are typically combined with a long-acting beta2 agonist in a regular treatment regimen.
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Investigators obtained participant identification numbers and randomized study drug assignments by using a Web-based or telephone call-in computerized drug management system.
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